Representative Publications
- Zhao Y, Wu X, Yang Y, Zhang L, Cai X, Chen S, Vera A, Ji J, Boström KI, Yao Y. Inhibition of endothelial histone deacetylase 2 shifts endothelial-mesenchymal transitions in cerebral arteriovenous malformation models. J Clin Invest. 2024 May 23;134(15). doi: 10.1172/JCI176758.
- Zhao Y, Yang Y, Wu X, Zhang L, Cai X, Ji J, Chen S, Vera A, Boström KI, Yao Y. CDK1 inhibition reduces osteogenesis in endothelial cells in vascular calcification. JCI Insight. 2024 Mar 8;9(5):e176065. doi: 10.1172/jci.insight.176065.
- Zhang L, Cai X, Ma F, Qiao X, Ji J, Ma JA, Vergnes L, Zhao Y, Yao Y, Wu X, Boström KI. Two-step regulation by matrix Gla protein in brown adipose cell differentiation. Mol Metab. 2024 Feb;80:101870. doi: 10.1016/j.molmet.2024.101870.
- Wu X, Zhang D, Qiao X, Zhang L, Cai X, Ji J, Ma JA, Zhao Y, Belperio JA, Boström KI, Yao Y. Regulating the cell shift of endothelial cell-like myofibroblasts in pulmonary fibrosis. Eur Respir J. 2023 Jun 8;61(6):2201799. doi: 10.1183/13993003.01799-2022.
- Yao J, Ma F, Zhang L, Zhu C, Jumabay M, Yao Z, Wang L, Cai X, Zhang D, Qiao X, Shivkumar K, Pellegrini M, Yao Y, Wu X, Boström KI. Single-Cell RNA-Seq Identifies Dynamic Cardiac Transition Program from ADCs Induced by Leukemia Inhibitory Factor. Stem Cells. 2022 Oct 21;40(10):932-948. doi: 10.1093/stmcls/sxac048.
- Yao J, Wu X, Qiao X, Zhang D, Zhang L, Ma JA, Cai X, Boström KI, Yao Y. Shifting osteogenesis in vascular calcification. JCI Insight. 2021 May 24;6(10):e143023. doi: 10.1172/jci.insight.143023.
- Zhang D, Qiao X, Yao J, Zhang L, Wu X, Ma J, Cai X, Bostrom KI, Yao Y. Pronethalol Reduces Sox2 (SRY [Sex-Determining Region Y]-Box 2) to Ameliorate Vascular Calcification. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):931-933. doi: 10.1161/ATVBAHA.120.315571.
- Guihard PJ, Guo Y, Wu X, Zhang L, Yao J, Jumabay M, Yao Y, Garfinkel A, Boström KI. Shaping Waves of Bone Morphogenetic Protein Inhibition During Vascular Growth. Circ Res. 2020 Oct 23;127(10):1288-1305. doi: 10.1161/CIRCRESAHA.120.317439. Epub 2020 Aug 28.
- Yao J, Wu X, Zhang D, Wang L, Zhang L, Reynolds EX, Hernandez C, Boström KI, Yao Y. Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations. J Clin Invest. 2019 Jun 24;129(8):3121-3133. doi: 10.1172/JCI125965.
- Yao J, Guihard PJ, Wu X, Blazquez-Medela AM, Spencer MJ, Jumabay M, Tontonoz P, Fogelman AM, Boström KI, Yao Y. Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017 Oct 2;216(10):3369-3385. doi: 10.1083/jcb.201612122.
- Yao J, Guihard PJ, Blazquez-Medela AM, Guo Y, Moon JH, Jumabay M, Boström KI, Yao Y. Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification. Circ Res. 2015 Oct 9;117(9):758-69. doi: 10.1161/CIRCRESAHA.115.306751.